Page 9 - Genetics_From_Genes_to_Genomes_6th_FULL_Part1

viii Contents

18.3 Targeted Mutagenesis 627 PART VII
18.4 Human Gene Therapy 634
■ Tools of Genetics: Cloning by Somatic Cell Nuclear Beyond the Individual Gene
Transfer 625 and Genome 713
■ Tools of Genetics: How Bacteria Vaccinate
Themselves Against Viral Infections with CRISPR/
Cas9 633
© Sue Flood/Oxford
■ Genetics and Society: Should We Alter Human Scientific/Getty Images
Germ-Line Genomes? 637
chapter 21

chapter 19 Variation and Selection in Populations 713
The Genetic Analysis of Development 646 21.1 The Hardy-Weinberg Law: Predicting Genetic
Variation in “Ideal” Populations 714
19.1 Model Organisms: Prototypes for
Developmental Genetics 647 21.2 What Causes Allele Frequencies to Change in
19.2 Mutagenesis Screens 649 Real Populations? 721
19.3 Determining Where and When Genes Act 654 21.3 Ancestry and the Evolution of Modern
Humans 731
19.4 Ordering Genes in a Pathway 657
19.5 A Comprehensive Example: Body Plan
Development in Drosophila 659 chapter 22

chapter 20 The Genetics of Complex Traits 746
22.1 Heritability: Genetic Versus Environmental
The Genetics of Cancer 681 Influences on Complex Traits 747
20.1 Characteristics of Cancer Cells 682 22.2 Mapping Quantitative Trait
20.2 The Genetic Basis of Cancers 684 Loci (QTLs) 757
20.3 How Cell Division Is Normally Controlled 687 ■ Tools of Genetics: The Chi-Square Test for
20.4 How Mutations Cause Cancer Independence 763
Phenotypes 694
20.5 Personalized Cancer Treatment 699 Guidelines for Gene Nomenclature A-1
■ Tools of Genetics: Analysis of Cell-Cycle Glossary G-1
Mutants in Yeast 691 Index I-1