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Contents vii
12.3 Chromosomal Packaging and Gene
Expression 414 PART V
12.4 Replication of Eukaryotic Chromosomes 419 How Genes Are
12.5 Chromosome Segregation 423 Regulated 547
12.6 Artificial Chromosomes 426
chapter 13 © SPL/Science Source
Chromosomal Rearrangements and Changes in chapter 16
Chromosome Number 436
Gene Regulation in Prokaryotes 547
13.1 Rearrangements of Chromosomal DNA 437 16.1 The Elements of Prokaryotic Gene
13.2 The Effects of Rearrangements 443 Expression 548
13.3 Transposable Genetic Elements 453 16.2 Regulation of Transcription Initiation
13.4 Aberrations in Chromosome Number: via DNA-Binding Proteins 549
Aneuploidy 460 16.3 RNA-Mediated Mechanisms of Gene
13.5 Variation in Number of Chromosome Sets: Regulation 562
Euploidy 465 16.4 Discovering and Manipulating Bacterial Gene
13.6 Genome Restructuring and Evolution 470 Regulatory Mechanisms 565
■ Fast Forward: Programmed DNA Rearrangements 16.5 A Comprehensive Example: Control of
and the Immune System 440 Bioluminescence by Quorum Sensing 570
chapter 14 chapter 17
Bacterial Genetics 487 Gene Regulation in Eukaryotes 583
14.1 The Enormous Diversity of Bacteria 488 17.1 Overview of Eukaryotic Gene Regulation 584
14.2 Bacterial Genomes 490 17.2 Control of Transcription Initiation Through
14.3 Bacteria as Experimental Organisms 495 Enhancers 585
14.4 Gene Transfer in Bacteria 497 17.3 Epigenetics 594
14.5 Using Genetics to Study Bacterial Life 509 17.4 Regulation After Transcription 600
14.6 A Comprehensive Example: How 17.5 A Comprehensive Example: Sex Determination
N. gonorrhoeae Became Resistant to in Drosophila 605
Penicillin 511
■ Tools of Genetics: The Gal4/UAS G Binary Gene
■ Genetics and Society: The Human Microbiome Expression System 592
Project 494
chapter 15 PART VI
Organellar Inheritance 521 Using Genetics 618
15.1 Mitochondria and Their Genomes 522
15.2 Chloroplasts and Their Genomes 525
15.3 The Relationship Between Organellar and
Nuclear Genomes 528
© Michael Goldberg, Cornell
15.4 Non-Mendelian Inheritance of Mitochondria University, Ithaca, NY
and Chloroplasts 530
15.5 Mutant Mitochondria and Human chapter 18
Disease 535 Manipulating the Genomes of Eukaryotes 618
■ Genetics and Society: Mitochondrial DNA Tests as
Evidence of Kinship in Argentine Courts 532 18.1 Creating Transgenic Organisms 619
18.2 Uses of Transgenic Organisms 622
■ Fast Forward: Mitochondrial Eve 536
