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Brief Contents











                1  Genetics: The Study of Biological
                   Information  1



                   PART I                                               PART IV

              Basic Principles: How Traits Are                     How Genes Travel on Chromosomes  406
              Transmitted   14
                                                                    12  The Eukaryotic Chromosome  406
                2  Mendel’s Principles of Heredity  14
                                                                    13  Chromosomal Rearrangements and Changes
                3  Extensions to Mendel’s Laws  45                      in Chromosome Number  436

                4  The Chromosome Theory of                         14  Bacterial Genetics  487
                   Inheritance  89
                                                                    15  Organellar Inheritance  521
                5  Linkage, Recombination, and the Mapping of
                   Genes on Chromosomes  133
                                                                        PART V

                   PART II                                         How Genes Are Regulated  547

              What Genes Are and What                               16  Gene Regulation in Prokaryotes  547
              They Do  181                                          17  Gene Regulation in Eukaryotes  583

                6  DNA Structure, Replication, and
                   Recombination  181
                                                                        PART VI
                7  Anatomy and Function of a Gene:
                   Dissection Through Mutation  219                Using Genetics   618

                8  Gene Expression: The Flow of                     18  Manipulating the Genomes of
                   Information from DNA to RNA to                       Eukaryotes  618
                   Protein  270
                                                                    19  The Genetic Analysis of Development  646

                                                                     20  The Genetics of Cancer  681
                   PART III

              Analysis of Genetic Information  316                      PART VII

                9  Digital Analysis of DNA  316                    Beyond the Individual Gene and Genome  713

               10  Genome Annotation  341                           21  Variation and Selection in Populations  713
               11  Analyzing Genomic Variation  365                  22  The Genetics of Complex Traits  746









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