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About the Authors
Dr. Leland Hartwell is President and Director of Seattle’s Fred Hutchinson Cancer Research
Center and Professor of Genome Sciences at the University of Washington.
Dr. Hartwell’s primary research contributions were in identifying genes that control cell divi-
sion in yeast, including those necessary for the division process as well as those necessary for the
fidelity of genome reproduction. Subsequently, many of these same genes have been found to
control cell division in humans and often to be the site of alteration in cancer cells.
Dr. Hartwell is a member of the National Academy of Sciences and has received the Albert
Lasker Basic Medical Research Award, the Gairdner Foundation International Award, the Genetics
Society Medal, and the 2001 Nobel Prize in Physiology or Medicine.
Dr. Michael Goldberg is a Professor at Cornell University, where he teaches introductory genet-
ics and human genetics. He was an undergraduate at Yale University and received his Ph.D. in
biochemistry from Stanford University. Dr. Goldberg performed postdoctoral research at the
Biozentrum of the University of Basel (Switzerland) and at Harvard University, and he received
an NIH Fogarty Senior International Fellowship for study at Imperial College (England) and fel-
lowships from the Fondazione Cenci Bolognetti for sabbatical work at the University of Rome
(Italy). His current research uses the tools of Drosophila genetics and the biochemical analysis of
frog egg cell extracts to investigate the mechanisms that ensure proper cell cycle progression and
chromosome segregation during mitosis and meiosis.
Dr. Janice Fischer is a Professor at The University of Texas at Austin, where she is an award-
winning teacher of genetics and Director of the Biology Instructional Office. She received her
Ph.D. in biochemistry and molecular biology from Harvard University, and did postdoctoral
research at The University of California at Berkeley and The Whitehead Institute at MIT. In her
research, Dr. Fischer used Drosophila first to determine how tissue-specific transcription works,
and then to examine the roles of ubiquitin and endocytosis in cell signaling during development.
Dr. Lee Hood received an M.D. from the Johns Hopkins Medical School and a Ph.D. in bio-
chemistry from the California Institute of Technology. His research interests include immunol-
ogy, cancer biology, development, and the development of biological instrumentation (for
example, the protein sequencer and the automated fluorescent DNA sequencer). His early research
played a key role in unraveling the mysteries of antibody diversity. More recently he has pioneered
systems approaches to biology and medicine.
Dr. Hood has taught molecular evolution, immunology, molecular biology, genomics and bio-
chemistry and has co-authored textbooks in biochemistry, molecular biology, and immunology, as
well as The Code of Codes—a monograph about the Human Genome Project. He was one of the
first advocates for the Human Genome Project and directed one of the federal genome centers that
sequenced the human genome. Dr. Hood is currently the president (and co-founder) of the cross-
disciplinary Institute for Systems Biology in Seattle, Washington.
Dr. Hood has received a variety of awards, including the Albert Lasker Award for Medical
Research (1987), the Distinguished Service Award from the National Association of Teachers
(1998) and the Lemelson/MIT Award for Invention (2003). He is the 2002 recipient of the Kyoto
Prize in Advanced Biotechnology—an award recognizing his pioneering work in developing the
protein and DNA synthesizers and sequencers that provide the technical foundation of modern
biology. He is deeply involved in K–12 science education. His hobbies include running, mountain
climbing, and reading.
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