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128    Chapter 4    The Chromosome Theory of Inheritance


                24.  In humans:                                      28.  A system of sex determination known as haplodip-
                  a.  How many sperm develop from 100 primary          loidy is found in honeybees. Females are diploid, and
                      spermatocytes?                                   males (drones) are haploid. Male offspring result
                  b. How many sperm develop from 100 secondary         from the development of unfertilized eggs. Sperm are
                                                                       produced by mitosis in males and fertilize eggs in the
                    spermatocytes?                                     females. Ivory eye is a recessive characteristic in
                  c.  How many sperm develop from 100 spermatids?        honeybees; wild-type eyes are brown.
                  d. How many ova develop from 100 primary oocytes?    a.  What progeny would result from an ivory-eyed
                  e.  How many ova develop from 100 secondary            queen and a brown-eyed drone? Give both geno-
                      oocytes?                                           type and phenotype for progeny produced from
                  f.  How many ova develop from 100 polar bodies?          fertilized and nonfertilized eggs.
                25.  Women sometimes develop benign tumors called      b. What would result from crossing a daughter from
                  ovarian teratomas or dermoid cysts in their ovaries.   the mating in part (a) with a brown-eyed drone?
                  Such a tumor begins when a primary oocyte escapes     29.  In Drosophila, the autosomal recessive brown eye
                  from its prophase I arrest and finishes meiosis I    color mutation displays interactions with both the
                  within the ovary. (Normally meiosis I does not fin-  X-linked recessive vermilion mutation and the au-
                  ish until the primary oocyte is expelled from the    tosomal recessive scarlet mutation. Flies homozy-
                  ovary upon ovulation.) The secondary oocyte then     gous for brown and simultaneously hemizygous or
                  develops as if it were an embryo. Development is     homozygous for vermilion have white eyes. Flies
                  disorganized, however, and results in a tumor        simultaneously homozygous for both the brown and
                    containing differentiated diploid tissues, including   scarlet mutations also have white eyes. Predict the
                  teeth, hair, bone, muscle, and nerve. If a dermoid   F 1  and F 2  progeny of crossing the following true-
                  cyst forms in a woman whose genotype is Aa, what     breeding parents:
                  are the possible genotypes of the cyst, assuming no   a.  vermilion females × brown males
                  recombination?                                       b. brown females × vermilion males
                26.  In a certain strain of turkeys, unfertilized eggs some-  c.  scarlet females × brown males
                  times develop parthenogenetically to produce diploid
                  offspring. (Females have ZW and males have ZZ sex    d. brown females × scarlet males
                  chromosomes. Assume that WW cells are inviable.)     30.  Barred feather pattern is a Z-linked dominant trait
                  What distribution of sexes would you expect to see   in chickens. What offspring would you expect from
                  among the parthenogenetic offspring according to     (a) the cross of a barred hen to a nonbarred rooster?
                  each of the following models for how parthenogenesis   (b) the cross of an F 1  rooster from part (a) to one of
                  occurs?                                              his sisters?
                  a.  The eggs develop from oogonial cells that never    31.  When Calvin Bridges observed a large number of off-
                    undergo meiosis.                                   spring from a cross of white-eyed female Drosophila to
                  b. The eggs go all the way through meiosis and then   red-eyed males, he found very rare white-eyed females
                    duplicate their chromosomes to become diploid.     and red-eyed males among the offspring. He was able
                  c.  The eggs go through meiosis I, and the chromatids   to show that these exceptions resulted from nondisjunc-
                                                                       tion, such that the white-eyed females had received two
                    separate to create diploidy.                       Xs from the egg and a Y from the sperm, while the
                  d. The egg goes all the way through meiosis and then   red-eyed males had received no sex chromosome from
                    fuses at random with one of its three polar bodies   the egg and an X from the sperm. What progeny would
                    (this scenario assumes the first polar body goes   have arisen from these same kinds of nondisjunctional
                    through meiosis II).                               events if they had occurred in the male parent? What
                                                                       would their eye colors have been?
              Section 4.6                                           32.  In a vial of Drosophila, a research student noticed
                27.  Imagine you have two pure-breeding lines of canaries,     several female flies (but no male flies) with bag wings
                  one with yellow feathers and the other with brown    each consisting of a large, liquid-filled blister instead
                  feathers. In crosses between these two strains, yellow   of the usual smooth wing blade. When bag-winged
                  female × brown male gives only brown sons and          females were crossed with wild-type males, 1/3 of the
                  daughters, while brown female × yellow male gives    progeny were bag-winged females, 1/3 were normal-
                  only brown sons and yellow daughters. Propose a      winged females, and 1/3 were normal-winged males.
                    hypothesis to explain these results.               Explain these results.
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