Page 47 - Genetics_From_Genes_to_Genomes_6th_FULL_Part1
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Problems   39




                                      PROBLEMS


                       Vocabulary                                              b. Which of these phenotypes is controlled by the
                         1.  For each of the terms in the left column, choose the   dominant allele?
                          best matching phrase in the right column.            c.  A normal-colored female snake is involved in a
                                                                                 testcross. This cross produces 10 normal-colored
                          a.  phenotype   1.  having two identical alleles of a given gene
                          b.  alleles     2.   the allele expressed in the phenotype of   and 11 albino offspring. What are the genotypes of
                                            the heterozygote                     the parents and the offspring?
                          c.  independent   3.  alternate forms of a gene      5.  Two short-haired cats mate and produce six short-
                            assortment                                         haired and two long-haired kittens. What does this in-
                          d.  gametes     4.  observable characteristic        formation suggest about how hair length is inherited?
                          e.  gene        5.   a cross between individuals both     6.  Piebald spotting is a condition found in humans in
                                            heterozygous for two genes
                          f.  segregation   6.   alleles of one gene separate into gametes   which there are patches of skin that lack pigmenta-
                                            randomly with respect to alleles of other   tion. The condition results from the inability of
                                            genes                                pigment-producing cells to migrate properly during
                          g.  heterozygote   7.   reproductive cells containing only one   development. Two adults with piebald spotting have
                                            copy of each gene                  one child who has this trait and a second child with
                          h.  dominant    8.   the allele that does not contribute to the   normal skin pigmentation.
                                            phenotype of the heterozygote      a.  Is the piebald spotting trait dominant or recessive?
                          i.  F 1         9.   the cross of an individual of ambiguous   What information led you to this answer?
                                            genotype with a homozygous recessive
                                            individual                         b. What are the genotypes of the parents?
                          j.  testcross   10.   an individual with two different alleles     7.  As a Drosophila research geneticist, you keep stocks
                                            of a gene                          of flies of specific genotypes. You have a fly that has
                          k.  genotype   11.   the heritable entity that determines a   normal wings (dominant phenotype). Flies with short
                                            characteristic
                          l.  recessive   12.   the alleles an individual has  wings are homozygous for a recessive allele of the
                                                                               wing-length gene. You need to know if this fly with
                          m. dihybrid cross   13.   the separation of the two alleles of a   normal wings is pure-breeding or heterozygous for
                                            gene into different gametes
                          n.  homozygote   14.  offspring of the P generation  the wing-length trait. What cross would you do to
                                                                                 determine the genotype, and what results would you
                       Section 2.1                                             expect for each possible genotype?
                         2.  During the millennia in which selective breeding was     8.  A mutant cucumber plant has flowers that fail to open
                          practiced, why did breeders fail to uncover the princi-  when mature. Crosses can be done with this plant by
                          ple that traits are governed by discrete units of inheri-  manually opening and pollinating the flowers with
                          tance (that is, by genes)?                           pollen from another plant. When closed × open
                         3.  Describe the characteristics of the garden pea that   crosses were done, all the F 1  progeny were open. The
                          made it a good organism for Mendel’s analysis of the   F 2  plants were 145 open and 59 closed. A cross of
                          basic principles of inheritance. Evaluate how easy or   closed × F 1  gave 81 open and 77 closed. How is the
                          difficult it would be to make a similar study of inheri-  closed trait inherited? What evidence led you to your
                          tance in humans by considering the same attributes   conclusion?
                          you described for the pea.                         9.  In a particular population of mice, certain individuals
                                                                               display a phenotype called short tail, which is inher-
                       Section 2.2                                             ited as a dominant trait. Some individuals display a
                         4.  An albino corn snake is crossed with a normal-colored   recessive trait called dilute, which affects coat color.
                          corn snake. The offspring are all normal-colored.    Which of these traits would be easier to eliminate
                          When these first-generation progeny snakes are       from the population by selective breeding? Why?
                          crossed among themselves, they produce 32 normal-    10.  In humans, a dimple in the chin is a dominant charac-
                          colored snakes and 10 albino snakes.                 teristic controlled by a single gene.
                          a.  How do you know that only a single gene is respon-  a.  A man who does not have a chin dimple has
                             sible for the color differences between these snakes?   children with a woman with a chin dimple whose
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